Igama lorhwebo | UniAPI-PBS |
CAS | 1405-20-5 |
Igama lemveliso | Polymyxin B sulfate |
Imbonakalo | Umgubo omhlophe okanye phantse omhlophe |
Ukunyibilika | Amanzi anyibilikayo |
Isicelo | Iyeza |
Isivavanyi | Isixa se-polymyxin B1, B2, B3 kunye ne-B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% max |
Iphakheji | 1kg net ngetoti yealuminiyam |
Beka ubomi kwishelufa | iminyaka eyi-2 |
Ugcino | Gcina kwindawo epholileyo neyomileyo, kude nokukhanya. 2 ~ 8℃ yokugcina. |
Ulwakhiwo lweMichiza |
Isicelo
I-Polyxin B sulfate yi-cationic surfactant antibiotics, umxube we-polyxin B1 kunye ne-B2, enokuphucula ukungeneka kwenwebu yeseli. Phantse ayinavumba. Inovakalelo ekukhanyeni. Hygroscopic. Inyibilika emanzini, inyibilika kancinane kwi-ethanol.
Isiphumo seklinikhi
I-antibacterial spectrum kunye nokusetyenziswa kweklinikhi kufana ne-polymyxin e. ineempembelelo ezithintelayo okanye iintsholongwane kwiibhaktheriya zeGram-negative, ezifana ne-Escherichia coli, i-Pseudomonas aeruginosa, i-paraescherichia coli, i-Klebsiella pneumoniae, i-acidophilus, i-pertussis kunye ne-dysentery. Ngokweklinikhi, isetyenziselwa ikakhulu usulelo olubangelwa ziibhaktheriya ezibuthathaka, usulelo lwenkqubo yomchamo olubangelwa yiPseudomonas aeruginosa, iliso, uqhoqhoqho, i-meningitis, i-sepsis, usulelo olutshisayo, ulusu kunye nosulelo lwenwebu yomchamo, njl.
isenzo samachiza
Inempembelelo ye-antibacterial kwi-Pseudomonas aeruginosa, i-Escherichia coli, i-Klebsiella pneumoniae, i-Haemophilus, i-enterobacter, i-Salmonella, i-Shigella, i-pertussis, i-pasteurella kunye ne-Vibrio. I-Proteus, i-Neisseria, i-Serratia, i-pruvidens, i-bacteria ye-Gram-positive kunye ne-obligate anaerobes ayizange ibe novelwano kula machiza. Bekukho ukuxhathisa okunqamlezayo phakathi kweli chiza kunye ne-polymyxin E, kodwa bekungekho ukuxhathisa okunqamlezayo phakathi kweli chiza kunye nezinye izibulala-ntsholongwane.
Isetyenziswa ikakhulu kwinxeba, umjelo womchamo, iliso, indlebe, usulelo loqhoqhoqho olubangelwa yiPseudomonas aeruginosa kunye nezinye iPseudomonas. Ingasetyenziselwa i-sepsis kunye ne-peritonitis.