Igama lorhwebo | Uni-Carbomer 974P |
Inombolo yeCAS. | 9003-01-04 |
INCI Igama | Carbomer |
Ulwakhiwo lweMichiza | |
Isicelo | Iimveliso ze-Ophthalmic, ii-Pharmaceutical formulations |
Iphakheji | I-20kgs inet ngebhokisi yekhadibhodi ene-PE lining |
Imbonakalo | Umgubo omhlophe |
Viscosity (20r/min, 25°C) | 29,400-39,400mPa.s (0.5% isisombululo samanzi) |
Ukunyibilika | Amanzi anyibilikayo |
Umsebenzi | Iiarhente zokutyebisa |
Beka ubomi kwishelufa | iminyaka eyi-2 |
Ugcino | Gcina isitya sivaliwe ngokuqinileyo kwaye kwindawo epholileyo. Gcina kude nobushushu. |
Umthamo | 0.2-1.0% |
Isicelo
I-Uni-Carbomer 974P idibana noshicilelo lwangoku lwemonographs ilandelayo:
EUnited States Pharmacopeia/National Formulary (USP/NF) monograph yeCarbomer Homopolymer Type B (Qaphela: I-USP/NF yangaphambili igama elixhasayo lale mveliso yayiyiCarbomer 934P.)
I-European Pharmacopeia (Ph. Eur.) imonograph yeCarbomer
I-China Pharmacopoeia (PhC.) imonograph yeCarbomer B
Ipropati ye-Applicaiton
Iimveliso ze-Uni-Carbomer 974P zisetyenziswe ngempumelelo kwiimveliso ze-ophthalmic kunye nokwakhiwa kwamachiza ukunika ukuguqulwa kwe-rheology, ukudibanisa, ukukhutshwa kweziyobisi okulawulwayo, kunye nezinye iipropati ezininzi ezizodwa.
I-1) Ubuhle obufanelekileyo kunye neempawu zovakalelo-yandisa ukuthotyelwa kwesigulana ngokucaphuka okuphantsi, iifomyula ezithandekayo ngovakalelo olufanelekileyo.
I-2) I-Bioadhesion / i-Mucoadhesion- yenza ukuhanjiswa kweziyobisi ngokwandisa uqhagamshelwano lwemveliso kunye ne-biological membranes, ukuphucula ukuthotyelwa kwesigulane ngesidingo esincitshisiweyo sokulawulwa rhoqo kweziyobisi, kunye nokukhusela kunye nokuthambisa ubuso be-mucosal.
3)Ukuguqulwa kweRheology esebenzayo kunye nokujiya kwi-semisolids yezihloko