| Igama lebrand: | I-Recombinant PDRN |
| Inombolo ye-CAS: | / |
| Igama le-INCI: | I-sodium DNA |
| Isicelo: | Iiloshini zokuthambisa eziphakathi ukuya kweziphezulu, iikhrimu, iziqwenga zamehlo, iimaski, njl.njl. |
| Iphakheji: | 50g |
| Inkangeleko: | Umgubo omhlophe |
| Inqanaba lemveliso: | Ibanga lokuhombisa |
| Ukunyibilika: | Iyanyibilika emanzini |
| i-pH (1% isisombululo samanzi): | 5.0 -9.0 |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Indawo yokugcina: | Gcina kwindawo epholileyo kude nelanga kubushushu begumbi |
| Idosi: | 0.01%-2.0% |
Isicelo
Imvelaphi ye-R&D:
I-PDRN yendabuko ikhutshwa kakhulu kwizicubu ze-salmon testicular. Ngenxa yokwahluka kobuchwephesha phakathi kwabavelisi, le nkqubo ayibizi nje kuphela kwaye ayizinzanga kodwa ikwanzima nokuqinisekisa ubunyulu bemveliso kunye nokuhambelana kwebhetshi nganye. Ngaphezu koko, ukuthembela kakhulu kwizixhobo zendalo kubeka uxinzelelo olukhulu kwindalo kwaye kuyasilela ukuhlangabezana neemfuno ezinkulu zemarike yexesha elizayo.
Ukwenziwa kwe-PDRN ephuma kwi-salmon ngendlela ye-biotechnology kuphumelela ukudlula imida yokukhupha izinto eziphilayo. Le ndlela ayiphuculi nje kuphela ukusebenza kakuhle kwemveliso kodwa ikwaphelisa ukuxhomekeka kwizixhobo eziphilayo. Ijongana nokuguquguquka komgangatho okubangelwa kukungcola okanye ukungcola ngexesha lokukhupha izinto, ifezekisa ukutsiba okukhulu kubunyulu bezinto, ukuhambelana kokusebenza kakuhle, kunye nokulawulwa kwemveliso, ngaloo ndlela iqinisekisa ukuveliswa okuzinzileyo nokunokwandiswa.
Iingenelo zobugcisa:
1. Ulandelelwano oluSebenzayo oluyilwe ngokuchanekileyo oluyi-100%
Ifezekisa ukuphindaphinda ngokuchanekileyo kolandelelwano olujoliswe kulo, yakha iimveliso ze-nucleic acid ezenzelwe wena ngokwenene "eziyilwe ngokusebenza kakuhle".
2. Ukungqinelana koBunzima beMolekyuli kunye nokuMiselwa kweSakhiwo
Ubude beqhekeza elilawulwayo kunye nolwakhiwo lolandelelwano luphucula kakhulu ukufana kweqhekeza lemolekyuli kunye nokusebenza kwe-transdermal.
3. Izinto Ezivela Kwizilwanyana Ezingekhoyo, Ezihambelana NeeNdlela Zolawulo Lwehlabathi
Iyandisa ukwamkelwa kwemarike kwiindawo ezibuthathaka zokusetyenziswa.
4. Amandla eMveliso yeHlabathi aZinzileyo nanokwanda.
Ngaphandle kwezixhobo zendalo, ivumela ukwandiswa okungenamkhawulo kunye nokuhanjiswa okuzinzileyo kwihlabathi liphela ngokusebenzisa iinkqubo zokubilisa eziphambili kunye nokucoca, ijongana ngokupheleleyo nemingeni emithathu ephambili ye-PDRN yendabuko: iindleko, uthotho lokubonelela, kunye nokuzinza kokusingqongileyo.
Izinto eziluhlaza ze-Recombinant PDRN zihambelana ngokugqibeleleyo neemfuno zophuhliso oluluhlaza noluzinzileyo lweebhrendi eziphakathi ukuya kweziphezulu.
Idatha yokusebenza kakuhle kunye nokhuseleko:
1. Ikhuthaza kakhulu ukulungiswa nokuhlaziywa:
Uvavanyo lwe-in vitro lubonisa ukuba imveliso iphucula kakhulu amandla okufuduka kweeseli, ibonisa ukusebenza kakuhle ekukhuthazeni imveliso ye-collagen xa kuthelekiswa ne-PDRN yendabuko, kwaye inika iziphumo ezibalaseleyo zokulwa nemibimbi kunye nokuqina.
2. Ukusebenza kakuhle kokulwa nokudumba:
Ithintela ngempumelelo ukukhululwa kwezinto eziphambili zokudumba (umz., i-TNF-α, i-IL-6).
3. Amandla angaqhelekanga okusebenzisana:
Xa idityaniswe ne-sodium hyaluronate (uxinzelelo: 50 μg/mL nganye), izinga lokufuduka kweeseli linokunyuka liye kuthi ga kwi-93% kwiiyure ezingama-24, nto leyo ebonisa amandla amahle okusetyenziswa ngokudibeneyo.
4. Uluhlu loQokelelo oluKhuselekileyo:
Izifundo ze-in vitro zibonisa ukuba i-100-200 μg/mL luluhlu loxinzelelo olukhuselekileyo nolusebenzayo olusetyenziswa kwihlabathi liphela, olulinganisa zombini imisebenzi yokwandisa (isiphumo esiphezulu kwiiyure ezingama-48-72) kunye nemisebenzi yokulwa nokuvuvukala.
5. Iphucula Ukuveliswa kweCollagen:
I-Recombinant PDRN ibonise ukwanda okuphindwe kayi-1.5 kwimveliso ye-type I collagen xa kuthelekiswa neqela lolawulo elingenanto, ngelixa ikwabonisa ukuphuculwa okuphindwe kayi-1.1 kwi-type III collagen synthesis.
