| Igama lebrand: | I-PromaCare LD1-PDRN |
| Inombolo ye-CAS: | 7732-18-5; 90046-12-1; /; 70445-33-9; 5343-92-0 |
| Igama le-INCI: | Amanzi; Isicatshulwa seLaminaria Digitata; I-Sodium DNA; I-Ethylhexylglycerin; I-Pentylene Glycol |
| Isicelo: | Imveliso yothotho oluthomalalisayo; Imveliso yothotho oluchasene nokudumba; Imveliso yothotho oluchasene nokwaluphala |
| Iphakheji: | 30ml/ibhotile, 500ml/ibhotile okanye ngokweemfuno zabathengi |
| Inkangeleko: | Ulwelo olukhanyayo olutyheli ukuya komdaka |
| Ukunyibilika: | Iyanyibilika emanzini |
| i-pH (1% isisombululo samanzi): | 4.0 – 9.0 |
| Umxholo we-DNA ppm: | imizuzu eli-1000 |
| Beka ubomi kwishelufa: | iminyaka eyi-2 |
| Indawo yokugcina: | Kufuneka igcinwe kwi-2~8°C kwisikhongozeli esivalwe kakuhle nesingenakukhanya. |
| Idosi: | 0.01 – 2% |
Isicelo
I-PromaCare LD1-PDRN sisiqwenga se-polysaccharides eziphakathi kweeseli kunye neziqwenga ze-DNA ezivela kwi-palmate kelp. Abalobi bokuqala baselunxwemeni bafumanisa ukuba i-kelp etyumkileyo inamandla akhethekileyo okukhuthaza ukugcinwa komswakama wesikhumba kunye nokulwa nokuvuvukala. Ngo-1985, ichiza lokuqala laselwandle i-sodium alginate laqanjwa laza lafakwa kwimveliso. Linemisebenzi yokulwa ne-antioxidant, yokulwa nokuvuvukala, yokulwa neentsholongwane, ukufuma kunye neminye, okwenza ukuba libe nekamva eliqaqambileyo kwicandelo lophando lwezonyango. Njengezinto eziluhlaza ze-cosmetic kunye ne-pharmaceutical, i-PDRN isetyenziswa kakhulu kubuhle bezonyango, iimveliso zemihla ngemihla zeekhemikhali, ukutya okunempilo kunye neminye imimandla. I-PromaCare LD1-PDRN yi-fucoidan kunye ne-deoxyribonucleic acid complex ekhutshwe kwiI-Laminaria japonicangenkqubo yokucoca engqongqo kwaye inokhuseleko oluphezulu kunye nozinzo.
I-PromaCare LD1-PDRN ibopha kwi-adenosine A2A receptor ukuze iqalise iindlela ezininzi zokubonisa iimpawu ezonyusa izinto ezichasene nokuvuvukala, zinciphise izinto ezibangela ukuvuvukala, kwaye zithintele iimpendulo ezibangela ukuvuvukala. Ikhuthaza ukwanda kwe-fibroblast, i-EGF, i-FGF, ukukhutshwa kwe-IGF, iphinda ibumbe imeko yangaphakathi yolusu olonakeleyo. Ikhuthaza i-VEGF ukuvelisa ii-capillaries, inike izondlo zokulungisa ulusu kunye nokukhupha izinto ezidala. Ngokubonelela nge-purine okanye i-pyrimidine njengendlela yokulungisa, ikhawulezisa ukwenziwa kwe-DNA kwaye ivumela ulusu ukuba luphinde lukhule ngokukhawuleza.
1. Uzinzo oludibeneyo
Ii-oligosaccharides ze-alginate zinokuthintela ngokupheleleyo (100%) i-lipid oxidation kwi-emulsions, nto leyo engcono ngama-89% kune-ascorbic acid.
2. Iimpawu zokulwa nokuvuvukala
I-oligosaccharide emdaka inokubopha kwi-selectins, ngaloo ndlela ithintele ukufuduka kweeseli ezimhlophe zegazi ukuya kwindawo enesifo, ngaloo ndlela ithintela uphuhliso lokudumba kwaye inciphise kakhulu ukurhawuzelelwa.
3. Nqanda i-apoptosis yeseli, i-anti-oxidation
I-oligosaccharide emdaka ye-alginate inokukhuthaza ukubonakaliswa kwe-Bcl-2 gene, ithintele ukubonakaliswa kwe-Bax gene, ithintele ukusebenza kwe-caspase-3 ebangelwa yi-hydrogen peroxide, kwaye ithintele ukuqhekeka kwe-PARP, nto leyo ebonisa impembelelo yayo yokuthintela kwi-apoptosis yeseli.
4. Ukugcinwa kwamanzi
I-oligosaccharide emdaka ineempawu ze-polymer ye-macromolecular, enokwanelisa zombini iimpawu zokwenza ifilimu kunye nezokuxhasa. Ngenxa yokusasazwa kwayo okufanayo kwe-macromolecular, ikwabonakalisiwe ukuba inokugcina amanzi kunye neempawu zokwenza ifilimu.
