Kwimeko ephucukileyo yokhathalelo lolusu olusebenzayo, iProtesse G66 ivela njengesisombululo esiphambili esidibanisa ukususwa kwesikhumba okuthambileyo kunye neenzuzo zokufumisa ezihlala zihleli. Iphuhliswe ngenkqubo yepapain ehlanganisiweyo kunye netekhnoloji yokukhulula eqhubekayo esekelwe kwi-sclerotium gum, iProtesse G66 iqinisekisa uzinzo lwe-enzyme, ukuhambelana, kunye nokuhanjiswa okulawulwayo ngaphakathi kweendlela zobuhle.
Itekhnoloji entsha yokusebenza okuzinzileyo nokuthambileyo
IProtesse G66 isebenzisa indlela "ye-4D" eyimfihlo—edibanisa ulungiselelo lwendawo olunemilinganiselo emithathu kunye nokukhululwa kwexesha—ukukhusela umsebenzi we-enzymatic we-papain ngelixa iphucula ukuhambelana kwayo neefomyula. Ukugquma kunciphisa ukudibana ngokuthe ngqo nezinto ezingqongileyo, kuphucula ukunyamezela kwe-papain kubushushu, i-pH, kunye nezinyibilikisi.
Ubungqina Bokusebenza Ngovavanyo Lwesayensi
Ukususwa kwesikhumba okuthambileyo: I-in vitro microscopic imaging ibonisa ukuba i-0.2% (w/v) Protesse G66 ikhuthaza i-hydrolysis yeprotheyini yomaleko we-keratin kwaye ibuyisela i-stratum corneum kwiiyure ezingama-48, ibonise ukukhupha i-foliation ngempumelelo ngaphandle kokubangela ukurhawuzelelwa.
Ukufuma Okuhlala Ixesha ElideUvavanyo lwe-In vivo lubonisa ukuba ijeli ye-5% yeProtesse G66 yonyusa ukufuma kolusu nge-13.9% emva kweeyure ezi-8, i-19.5% emva kweeyure ezingama-24, kunye ne-29.3% emva kweentsuku ezingama-28.
Ukuhlaziywa kweeSeli ezixhomekeke kuXinzeleloUvavanyo lwe-Ex vivo desquamation lubonisa ukuba iProtesse G66 iphucula ukususwa kweekeratinocytes ezindala ngokulinganayo ukuze zihlale ziqinile, nto leyo ephucula ukukhanya kunye nokuthungwa kolusu.
Izicelo kunye nokuguquguquka
IProtesse G66 ifanelekile kwiintlobo ngeentlobo zeefomyula, kuquka iikhrimu zokucoca, iiserum, amanzi acocekileyo, iimaski, kunye nezicoci. Iprofayili yayo ezinzileyo nethambileyo yenza ukuba ibe lukhetho olufanelekileyo kwiimveliso zokhathalelo lolusu ezisebenza kakuhle neziqhutywa yisayensi.
Isiphelo
Ngokudibanisa i-papain ne-sclerotium gum kwi-matrix yokukhululwa elawulwayo,IProtesse G66Ibonelela ngokucoca ulusu ngendlela esebenzayo, ulusu luphuculwe, kunye nomswakama ohlala ixesha elide ngelixa igcina uzinzo lokwakheka. Le ndlela intsha igxininisa amandla obuchwepheshe bokufaka ii-capsulation kukhathalelo lolusu lwanamhlanje kwaye inika iimpawu i-active ethembekileyo, eguquguqukayo kwizicelo zokuhombisa ezisebenzayo.
Ixesha lokuthumela: Jan-09-2026