Iingcali zenzululwazi ziye zafumanisa ukuba i-3-O-ethyl ascorbic acid, eyaziwa ngokuba yi-EAA, iyimveliso yendalo ene-antioxidant kunye ne-anti-inflammatory properties, inokuba nezicelo ezinokuthi zisebenzise amayeza kunye nezongezelelo zempilo.
Uphando olwenziwe kwiYunivesithi yaseCalifornia, eLos Angeles (UCLA) lufumene ukuba i-3-O-ethyl ascorbic acid, idlala indima ebalulekileyo ekukhuseleni iiseli kuxinzelelo lwe-oxidative kunye nokudumba. Ngokungafani ne-vitamin C eqhelekileyo, efakwe ngokukhawuleza emzimbeni kwaye isuswe, i-EAA ithatha ngokukhawuleza kwaye ihlala emzimbeni ixesha elide, inika ukhuseleko oluqhubekayo kwi-radicals yamahhala kunye nokuvuvukala.
Uphononongo, olupapashwe kwijenali yeNdalo, lucebisa ukuba i-EAA inokuphuhliswa ibe lunyango olunokubakho kwizifo ezahlukeneyo eziphawulwa luxinzelelo lwe-oxidative kunye nokudumba, njengomhlaza, izifo zentliziyo, kunye nokuphazamiseka kwe-neurodeergenerative. Ukongeza, i-EAA inokuba nezicelo kwishishini lokuthambisa njengesithako esichasene nokuguga ngenxa yokukwazi ukukhusela uxinzelelo lwe-oxidative kunye nokudumba.
Kwinkqubela phambili, abaphandi baye bafumanisa ukuba i-3-O-ethyl ascorbic acid ether, eyaziwa ngokuba yi-vitamin C ethyl ether, inokunika isisombululo kwimida ye-vitamin C yendabuko kwizicelo zokuthambisa. Ngenxa yobukho bamaqela amane e-hydroxyl kwisakhiwo sayo, ivithamin C ngokwayo ayikwazi ukufunxwa ngokuthe ngqo lusu kwaye iyathandeka kwi-oxidation, ibangela ukuguquka kombala. Oku kuthintele ukusetyenziswa kwayo njengearhente yokwenza mhlophe kwizinto zokuthambisa. Ngaphezu koko, izazinzulu ziye zafumanisa ukuba ivithamin C ethyl ether, efunyenwe nge-alkylating iqela le-3-position hydroxyl, i-derivative non-discoloring derivative ye-vitamin C egcina umsebenzi wayo webhayoloji. Oku kufunyanisiweyo kuzalisa isithuba kwimarike yeemveliso ezifanayo. Iziphumo ezikhuthazayo ezivela kwizifundo zibonisa ukuba i-vitamin C ethyl ether ichithwa ngokulula yi-enzymes xa ingena esikhumbeni, ivumela ukuba izalisekise indima efanayo ne-vitamin C ekukhuthazeni impilo yesikhumba kunye nokuba mhlophe.
I-Uniproma ibonelela ngekhwalithi ephezuluPromaCare EAAkwiimarike zehlabathi iminyaka emininzi kwaye imveliso iyaziwa kwimarike yokusebenza okuphezulu kunye nokuzinza okulungileyo.
Ixesha lokuposa: Jan-09-2024