I-ActiTide™ Bouncera imele inkqubela phambili ebalulekileyo kwizithako zobuhle ezisekelwe kwi-peptide, inikezela ngesisombululo esinobuchule sokulwa nokwaluphala esenzelwe ukoyisa imida yembali ye-peptide bioavailability. Ngelixa ii-peptides zidume ngokukwazi kwazo ukubonisa izinto eziphilayo, ukusetyenziswa kwazo kudla ngokuthintelwa yi-hydrophilicity ephezulu kunye nobukhulu obukhulu beemolekyuli, okuthintela amandla azo okungena kwi-corneum yesikhumba etyebileyo kwi-lipid. I-ActiTide™ Bouncera ijongana nale mingeni ngokudibanisa i-synergistic triple-peptide complex kunye netekhnoloji yokuhambisa ephucukileyo.
Ukoyisa Imiqobo Yokuhambisa NgeTekhnoloji yeSupramolecular
Iifomyula ze-peptide zemveli zihlala zinengxaki yokufunxwa kakubi kwe-transdermal, nto leyo ebangela ukuba izithako ezisebenzayo zihlale kumphezulu wesikhumba zingafikeleli kwiileya zesikhumba ekujoliswe kuzo. I-ActiTide™ Bouncera isombulula oku ngokusebenzisa iTekhnoloji ye-Supramolecular Synergistic Penetration, equka i-DES-TG supramolecular ionic liquids.
Le ndlela intsha idala inkqubo yokuhambisa edibeneyo apho iipeptide—iPalmitoyl Tripeptide-5, iHexapeptide-9, kunye neHexapeptide-11—zihlelwe zaba yi-supramolecular complex. Le teknoloji iguqula ukungena komqobo wolusu ngendlela elawulwayo ne "ehambelana nolwakhiwo", iqinisekisa ukuba izinto ezisebenzayo ziqhutywa ngokufanelekileyo kwi-epidermis enzulu kunye ne-dermis ngaphandle kokuphazamisa ukuqina kwendalo kolusu.
Ukungena Okuqinisekisiweyo kunye nokufumaneka kwezinto eziphilayo
Ubuchule bobuchwephesha be-ActiTide™ Bouncera buqinisekiswa zizifundo ezingqongqo zokungena kwesikhumba kwi-vitro. Kusetyenziswa iteknoloji yokulandelela i-fluorescence tracer ephucukileyo, iipropati zokungena kweepeptides nganye ngaphakathi kwi-complex zivavanyiwe. Olu phononongo lubonise ukuba i-ActiTide™ Bouncera ifikelela kubunzulu bokungena obuphindwe kathathu ukuya kahlanu kunobo beqela lolawulo kwi-peptide nganye nganye. I-Fluorescence imaging iqinisekisile ukujoliswa kwesikhumba okunzulu, iqinisekisa ukuba izithako ezisebenzayo ze-biopeptide zifikelela kwi-fibroblasts kunye ne-Dermal-Epidermal Junction (DEJ) apho zinokusebenza khona kakhulu.
Ukusebenza Okujolise Kwiinjongo Ezininzi kunye Nokwakhiwa Kabutsha Kwesikhumba
Ngaphandle kokunikezelwa kwayo okuphezulu, i-ActiTide™ Bouncera ibonisa ukusebenza okunzulu kwezinto eziphilayo kwiindlela ezininzi zokwaluphala kwizifundo zovavanyo:
Inkxaso yoLwakhiwo lwe-DEJ: Inyusa kakhulu ukubonakaliswa kwezakhi zofuzo zeCollagen IV kunye neVII, iiproteni ezibalulekileyo zokuqinisa iDermal-Epidermal Junction kunye nokubuyisela inkxaso yesiseko solusu.
Ukwenziwa kweCollagen: Kwiimvavanyo zokusebenza kakuhle, uxinaniso lwe-0.15% kuphela lukhuthaze ukwenziwa kweCollagen yohlobo I nge-332.32%, nto leyo ebonisa amandla anamandla okuqinisa ulusu kunye nokunciphisa ubunzulu bemibimbi.
Ukuthintela ukonakala kwe-collagen kunye nokulahleka kwe-collagen: Inika isikhuselo esomeleleyo sokuzikhusela ngokuthintela i-MMP-1 (i-enzyme enoxanduva lokonakala kwe-collagen). Ngoxinzelelo lwe-0.10%, amanqanaba e-MMP-1 ancitshiswe ngama-94.66%, nto leyo ephumelela ngaphezu kweVithamin C xa kuthelekiswa.
Iimpawu zeFizikokhemikhali kunye nezicelo
Ngokwefiziksi, i-ActiTide™ Bouncera lulwelo olungenambala okanye olukhanyayo, oluyilelwe ukuzinza okuphezulu kunye nokulula kokwenziwa. Ihambelana kakhulu neemveliso ezahlukeneyo zokhathalelo lolusu olukumgangatho ophezulu, kubandakanya iiserum eziphezulu, iikhrimu zokuqinisa, kunye neemaski zokuvuselela. Idosi ecetyiswayo ye-0.2–5.0% ivumela ukusetyenziswa okuguquguqukayo kwiifomyula ezijolise ekunciphiseni imibimbi enzulu kunye nokuvuselelwa kolusu.
Ngamafutshane, i-ActiTide™ Bouncera ibonakalisa inkqubela phambili kwezobuchwepheshe ukusuka kwisicelo se-peptide esiqhelekileyo ukuya ekunikezelweni kwe-biotechnology okuphucukileyo. Ngokudibanisa ukuchaneka kwe-triple-peptide complex kunye namandla e-Supramolecular Synergistic Penetration, ibonelela ngesisombululo esicocekileyo nesisebenza kakuhle kwisizukulwana esilandelayo sokhathalelo lolusu oluchwephesha. Ukhuseleko lwayo olubonakalisiweyo, amandla okungena ngokunzulu (ukufikelela amaxesha ama-3-5 ekungeneni kolawulo oluqhelekileyo), kunye nokusebenza okumangalisayo kuyibeka njengesithako esibalulekileyo kwiimveliso ze-cosmetic zehlabathi ezifuna iziphumo eziqinisekisiweyo ngokwesayensi.
Ixesha lokuthumela: Jan-07-2026