| Igama lebrand | I-ActiTid™ e-AH3 (enyibilikisiweyo 500) |
| Inombolo ye-CAS | 7732-18-5; 616204-22-9; 1117-86-8 |
| Igama le-INCI | Amanzi; I-Acetyl hexapeptide-8; I-Caprylyl glycol |
| Isicelo | Iloshini, iiSerum, iMask, isicoci sobuso |
| Iphakheji | 1kg/ibhotile |
| Inkangeleko | Ulwelo olucacileyo nolubonakalayo |
| Umxholo wePeptide | 0.045 – 0.060% |
| Ukunyibilika | Amanzi anyibilikayo |
| Umsebenzi | Uthotho lwePeptide |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Indawo yokugcina izinto | Gcina kwindawo epholileyo neyomileyo, kude nokukhanya. 2~8°C ukuze ugcine |
| Idosi | 3.0-10.0% |
Isicelo
Uphando malunga neendlela ezisisiseko zokulwa nemibimbi lukhokelele ekufumanekeni kwe-ActiTide™ AH3, i-hexapeptide entsha eyenziwe ngendlela yesayensi ukusuka kuyilo oluqiqileyo ukuya kwimveliso ye-GMP, eneziphumo ezilungileyo.
I-ActiTide™ AH3 inika ukusebenza okuncitshisa imibimbi okufana nohlobo lweBotulinum Toxin Type A, ngelixa ithintela iingozi zokujova kwaye inika ixabiso eliphantsi.
Iingenelo zobuhle:
I-ActiTide™ AH3 inciphisa ubunzulu bemibimbi ebangelwa kukuxinana kwemisipha yobuso, nto leyo echaphazela ibunzi kunye nemibimbi ye-periocular.
Indlela Yokusebenza:
Ukuxinana kwemisipha kwenzeka xa i-neurotransmitter ikhutshwa kwi-synaptic vesicles. I-SNARE complex – i-ternary assembly ye-VAMP, Syntaxin, kunye ne-SNAP-25 proteins – ibalulekile kwi-vesicle docking kunye ne-neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272:2634-2638). Le complex isebenza njenge-cellular hook, ibamba ii-vesicles kwaye iqhube i-membrane fusion.
Njengomzekelo wesakhiwo se-SNAP-25 N-terminus, i-ActiTide™ AH3 ikhuphisana ne-SNAP-25 ukuze ifakwe kwi-SNARE complex, nto leyo eguqula ukuhlanganiswa kwayo. Ukuphazamiseka kwe-SNARE complex kuphazamisa ukuvalwa kwe-vesicle kunye nokukhululwa kwe-neurotransmitter okulandelayo, okukhokelela ekunciphiseni ukuxinana kwemisipha kunye nokuthintela ukwakheka kwemibimbi kunye nomgca omncinci.
I-ActiTide™ AH3 yindlela ekhuselekileyo, engabizi kakhulu, nethambileyo endaweni yeBotulinum Toxin Type A. Ijolise ngqo kwindlela efanayo yokwakheka kwemibimbi kodwa isebenza ngendlela eyahlukileyo.
