| Igama lebrand | ActiTide-AH3(Liquefied 1000) |
| Inombolo yeCAS. | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| INCI Igama | I-Acetyl Hexapeptide-8; IGlycerin; Butylene Glycol; Amanzi; Hydroxyacetophenone; 1,2-Hexanediol |
| Isicelo | I-Lotion, iiSerum, iMask, isicoci sobuso |
| Iphakheji | 1kg/ibhotile |
| Imbonakalo | Ulwelo olucacileyo olucacileyo kunye nevumba elibonakalayo |
| Ukunyibilika | Amanzi anyibilikayo |
| Umsebenzi | Peptide series |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ugcino | Gcina isikhongozeli sivalwe ngokuqinileyo kwindawo epholileyo, eyomileyo kwi-2 - 8°C. |
| Umthamo | 3.0-10.0% |
Isicelo
Uphando kwiindlela ezisisiseko zokulwa nemibimbi lukhokelele ekufunyanweni kwe-ActiTide-AH3, i-hexapeptide entsha ephuhliswe ngendlela yenzululwazi ukusuka kuyilo oluqiqileyo ukuya kwimveliso ye-GMP, eneziphumo ezilungileyo.
I-ActiTide-AH3 ihambisa ukusebenza kakuhle kokunciphisa imibimbi ngokuthelekiswa ne-Botulinum Toxin Type A, ngelixa ikhusela umngcipheko wokutofa kunye nokubonelela ngeendleko eziphezulu.
Izibonelelo zokuthambisa:
I-ActiTide-AH3 inciphisa ubunzulu bokushwabana okubangelwa kukufinyaniswa kwemisipha yobuso, kunye neziphumo ezivakalayo kwibunzi kunye nemibimbi yeperiocular.
Indlela yokwenza:
Ukucutheka kwezihlunu kwenzeka ekukhutshweni kwe-neurotransmitter kwi-synaptic vesicles. I-SNARE complex - indibano ye-ternary ye-VAMP, i-Syntaxin, kunye ne-SNAP-25 iiprotheni - ibalulekile kwi-vesicle docking kunye ne-neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Olu bunzima lusebenza njenge-hook yeselula, ukubamba i-vesicles kunye nokuqhuba i-membrane fusion.
Njengomfanekiso wesakhiwo se-SNAP-25 N-terminus, i-ActiTide-AH3 ikhuphisana ne-SNAP-25 yokufakwa kwi-SNARE complex, imodareyitha indibano yayo. Ukuchithwa kwe-SNARE eyinkimbinkimbi yonakalisa i-vesicle docking kunye nokukhululwa kwe-neurotransmitter elandelayo, okukhokelela ekunciphiseni ukunyanzeliswa kwemisipha kunye nokuthintela imibimbi kunye nokuqulunqwa komgca ococekileyo.
I-ActiTide-AH3 yindlela ekhuselekileyo, eyongayo, kwaye ethambileyo kune-Botulinum Toxin Type A. Ijolise ngokwesihloko kwindlela yokubumba imibimbi kodwa isebenza ngendlela eyahlukileyo.
