| Igama lebrand | I-ActiTide-AH3 |
| Inombolo yeCAS. | 616204-22-9 |
| INCI Igama | I-Acetyl Hexapeptide-3 |
| Ulwakhiwo lweMichiza |  |
| Isicelo | Lotion, iiserum, imaski, isicoci sobuso |
| Iphakheji | 1kg net ngebhotile /20kgs net igubu ngalinye |
| Imbonakalo | Ulwelo/umgubo |
| I-Acetyl hexapeptide-3(8) (Ulwelo) | 450-550ppm 900-1200ppm |
| Ubunyulu (Umgubo) | 95% imizuzu |
| Ukunyibilika | Amanzi anyibilikayo |
| Umsebenzi | Peptide series |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ugcino | Gcina kwindawo epholileyo neyomileyo, kude nokukhanya. 2~8℃yokugcina. |
| Umthamo | 2000-5000ppm |
Isicelo
I-anti-wrinkle hexapeptide ActiTide-I-AH3 imele ukufunyanwa kokubetha okulungileyo okusekwe kwindlela yenzululwazi ukusuka kuyilo oluqiqileyo ukuya kwimveliso ye-GMP. Uphononongo lweendlela ezisisiseko zebhayoloji zomsebenzi wokuchasana nemibimbi kukhokelele kule hexapeptide yenguquko eye yathatha ilizwe lezobuhle ngoqhwithela.
Okokugqibela, unyango lokushwabana olunokukhuphisana nokusebenza kweBotulinum Toxin A kodwa lushiya bucala iingozi, iinaliti kunye neendleko eziphezulu: ActiTide-AH3.
Izibonelelo zokuthambisa:
I-ActiTide-AH3 inciphisa ubunzulu bemibimbi ebangelwa kukucutheka kwemisipha yembonakalo yobuso, ngakumbi ebunzi nakufutshane namehlo.
Isebenza njani i-ActiTide-AH3?
Izihlunu zibanjwa xa zifumana i-neurotransmitter ehamba ngaphakathi kwe-vesicle. I-SNARE (i-SNAp RE ceptor) i-complex iyimfuneko ekukhululweni kwe-neurotransmitter kwi-synapsis (A. Ferrer Montiel et al, I-Journal ye-Biological Chemistry, i-1997, i-272, i-2634-2638). I-ternary complex eyenziwa yi-proteins i-VAMP, i-Syntaxin kunye ne-SNAP-25. Le nto inzima ifana nekhonkco yeselula ebamba i-vesicles kwaye idibanise kunye ne-membrane yokukhululwa kwe-neurotransmitter.
I-ActiTide-AH3 ifana ne-N-terminal end ye-SNAP-25 ekhuphisana ne-SNAP-25 kwisithuba kwi-SNARE complex, ngaloo ndlela imodareyitha ukubunjwa kwayo. Ukuba i-SNARE i-complex igxininiswe kancinci, i-vesicle ayikwazi ukukhwela kwaye ikhulule i-neurotransmitters ngokufanelekileyo kwaye ngoko ke i-muscle contraction iyancipha, ikhusela ukubunjwa kwemigca kunye nemibimbi.
I-ActiTide-AH3 yeyona ndlela ikhuselekileyo, inexabiso eliphantsi, kunye nethambileyo kwi-Botulinum Toxin, ijolise phezulu kwindlela yokubumba imibimbi ngendlela eyahlukileyo kakhulu.
